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 About 2 results found for searched term "CX-5461" (0.125 seconds)

Cat.No.  Name Target
M2293 CX-5461 DNA/RNA Synthesis
Pidnarulex
CX-5461 (Pidnarulex) selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116 cells.
M13642 CX-5461 dihydrochloride DNA/RNA Synthesis
CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).



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