About 4 results found for searched term "CRM1-IN-2" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42175 | CRM1-IN-2 | CRM1 |
| CRM1-IN-2 is a noncovalent CRM1 inhibitor. | ||
| M9909 | Eltanexor | CRM1 |
| KPT-8602 | ||
| Eltanexor, also known as KPT-8602, is a second-generation exportin-1 (CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines. | ||
| M21722 | Felezonexor (CBS9106) | CRM1 |
| CBS9106; SL-801 | ||
| Felezonexor (CBS9106; SL-801) is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity without affecting CRM1 mRNA levels. Felezonexor is also a reversible inhibitor of XPO1, inhibits nuclear export by covalently binding to Cys528 as well as by inducing the degradation of XPO1. | ||
| M28308 | KPT-251 | CRM1 |
| KPT-251 is an orally active chromosome region maintenance 1 protein (CRM1) inhibitor. KPT-251 induces cancer cell apoptosis and shows antileukemic activity. | ||
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