About 30 results found for searched term "CHES" (0.149 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6593 | CHES | Others |
| CHES is a buffering agent. | ||
| M17308 | Ducheside A | Phenols |
| Ducheside A | ||
| M3671 | Cyclophosphamide monohydrate | Animal Modeling |
| Cyclophosphamide hydrate | ||
| Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M4468 | Cinnamyl-alcohol | PPAR |
| Cinnamyl Alcohol isolated from Chestnut flower showed anti-obesity activity by inhibiting the expression of PPARγ. | ||
| M4566 | Escin-IA | HIV Protease |
| Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation. | ||
| M4567 | Escin-IB | Others |
| Escin IB is a saponin isolated from the skin and endosperm of horse chestnut (Aesculus hippocastanum) seeds. Escin IB has an inhibitory effect on pancreatic lipase activity. | ||
| M4568 | Aescin-IIA | Others |
| Escin IIa, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIa has obvious protective effect on gastric mucosa injury induced by ethanol. | ||
| M4569 | AescinIIB | Others |
| Escin IIb, isolated from horse chestnut seed horse chestnut, has a positive effect on acute inflammation in animals. Escin IIb has a significant protective effect on gastric mucosa injury induced by ethanol. | ||
| M5139 | Amlodipine | Calcium Channel |
| UK-48340 | ||
| Amlodipine is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. | ||
| M5411 | Amlodipine Besylate | Calcium Channel |
| Amlodipine benzenesulfonate | ||
| Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. | ||
| M5426 | Aspirin | Animal Modeling |
| Acetylsalicylic acid | ||
| Aspirin is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. | ||
| M5556 | DEET | Parasite |
| Diethyltoluamide; N,N-Diethyl-m-toluamide | ||
| DEET is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. | ||
| M5623 | Escin | Apoptosis |
| Aescin | ||
| Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut). | ||
| M8615 | Ribocil-C | Others |
| Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches. | ||
| M11140 | Protoescigenin | Others |
| Protoescigenin is the main glycoside of the horse chestnut saponin mixture. Protoescigenin can be used as a substrate for exploratory chemical reactions for selective protection, followed by the formation of propyl ethers, which are subsequently condensed with azido-monosaccharides to obtain new triterpenetriazole-linked conjugates. | ||
| M14036 | Orexin A (human, rat, mouse) (TFA) | OX Receptor |
| Orexin A human, rat, mouse TFA, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. | ||
| M21047 | Diethyl phosphate | IL Receptor/Related |
| DEP, DPF, Diethyl phosphoric acid, diethyl hydrogen phosphate | ||
| Diethyl phosphate (DEP, DPF, Diethyl phosphoric acid, diethyl hydrogen phosphate), a non-specific metabolite of organophosphorus pesticides in the gut environment, significantly enriches opportunistic pathogens leading to a decrease in interleukin-6 (IL-6). | ||
| M25205 | Siplizumab | Others |
| MEDI-507 | ||
| Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells. | ||
| M25562 | TTK21 | Histone Acetyltransferase |
| TTK-21 | ||
| TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 can cross the blood-brain barrier, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has potential for research of brain neurogenesis and long-term memory function. | ||
| M28295 | Ribocil | Antibiotic |
| Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3 μM. Target: in vitro: Ribocil is a highly specific bioactive synthetic mimic of FMN, which competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB and inhibits bacterial growth. Ribocil-B demonstrates superior microbiological activity as compared to Ribocil-A (minimum inhibitory concentration (MIC) = 1 μg/ml versus MIC ≥ 64 μg/ml), inhibition of riboflavin synthesis (IC50 = 0.13 μM versus IC50 > 26 μM), and binding affinity to the E. coli FMN aptamer (Kd = 6.6 nM versus Kd ≥ 10,000 nM).[1] | ||
| M30206 | 1,3,5,6-Tetrahydroxyxanthone | Others |
| 1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats. | ||
| M30670 | Spiraprilat | ACE |
| Spiraprilat is a potent angiotensin-converting enzyme (ACE) inhibitor. Spiraprilat has ability to improve left ventricular (LV) function and metabolism in anesthetized open-chest dogs with acute ventricular failure (ALVF). | ||
| M38721 | Sequosempervirin B | Antifungal |
| Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase. | ||
| M39008 | (+)-Ochromycinone | STAT |
| (+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis. | ||
| M40349 | Lansiumarin C | Others |
| Lansiumarin C, a lansiumarin, can be isolated from the branches of Clausena lansium (Rutaceae). | ||
| M40460 | Odorinol | Others |
| Odorinol is a natural product isolated from branches and leaves of Aglaia odorata. Odorinol has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer. | ||
| M40470 | Odorine | Others |
| Odorine (Roxburghiline) is a natural product isolated from branches and leaves of Aglaia odorata. Odorine has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer. | ||
| M43849 | Laminaran | Others |
| Laminaran is a β-1-3-glucan from Eisenia Bicyclis, consisting of β(1→3)-glucans with β(1→6) branches, which can be catalyzed by glucoamylases such as (EC 3.2.1.6). Laminaran is also a typical ligand for Dectin-1, which has immunomodulatory, radioprotective and anticancer activities. It can be used in cancer immunity studies. | ||
| M50493 | Hirugen | Others |
| Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches. | ||
| M51595 | Tetanus toxin (830-843) | Others |
| Tetanus toxin (830-843) is a powerful neurotoxin that reaches by retroaxonal transport and transcytosis the cytoplasm ofspinal inhibitory intemeurons and blocks their ability to release neurotransmitters. | ||
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