About 5 results found for searched term "CB 65" (0.074 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6564 | CB 65 | Others |
| CB 65 is a high affinity, selective CB 2 agonist. | ||
| M9421 | Parsaclisib | PI3K |
| INCB050465 | ||
| Parsaclisib (INCB050465) is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP. | ||
| M11354 | INCB086550 | PD-1/PD-L1 |
| PD-1/PD-L1-IN-8 | ||
| INCB086550 selectively inhibited PD-L1 with IC50 of 3.1 nM, 4.9 nM and 1.9 nM for human, rhesus monkey and rat pD-L1, respectively. INCB086550 could not inhibit the binding of PD-L2 to PD-1 at 10 μM. INCB086550 significantly inhibits the PD-1/PD-L1 signaling axis by binding to PD-L1 protein, leading to PD-L1 dimerization and internalization, and has good tumor suppressive effect in a variety of mouse tumor models. | ||
| M22034 | CB30865 | Others |
| CB30865 | ||
| M24723 | Rozanolixizumab | Others |
| UCB7665 | ||
| Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases. | ||
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