About 2 results found for searched term "Belnacasan" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3532 | Belnacasan | Caspase |
| VX-765 | ||
| Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM. | ||
| M13536 | VRT-043198 | Caspase |
| VRT-043198, the drug metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. | ||
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