About 1 result found for searched term "Avatrombopag maleate" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30468 | Avatrombopag maleate | Thrombopoietin/Thrombin |
| AKR-501 maleate; E5501 maleate; YM477 maleate | ||
| Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A. | ||
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