About 31 results found for searched term "Ara-SH" (0.105 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41306 | Ara-SH | Apoptosis |
| Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. | ||
| M13353 | Phosphatidylcholines,soya | Liposome |
| Soybean phosphatidylcholine | ||
| Phosphatidylcholines, soya is a kind of extracted from soybean phosphatidyl choline, can be used for the preparation of liposomes. Has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. Phosphatidylcholines, soya can be used as animal drug delivery carrier. | ||
| M2882 | (-)-Nicotine ditartrate | Others |
| (-)-Nicotine ditartrate is a potent parasympathomimetic alkaloid found in the nightshade family of plants (Solanaceae), and also a nicotinic acetylcholine receptor agonist. | ||
| M3400 | Idebenone | Ferroptosis |
| CV-2619 | ||
| Idebenone, a mitochondrial protector, has neuroprotective properties and can be used to study Alzheimer's disease, Huntington's disease, and can cross the blood-brain barrier. Idebenone (oxidized form) inhibited arachidonic acid enzyme metabolism in astrocyte homogenates (IC50=16.65 μM). Idebenone is a coenzyme Q10 analogue and antioxidant that induces apoptosis (apoptotic) in human dopaminergic neuroblastoma SHSY-5Y cells. | ||
| M4448 | Acetylcimigenol-3-O-α-L-arabinopyranside | Others |
| Acetylshengmanol -3-O-α -L-arabinose is an extract of cohosh. | ||
| M4523 | Specnuezhenide | NF-κB |
| Specnuezhenide ((8E)-Nuezhenide) was separated from the fruit of the ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) inhibited IL-1β -induced chondrocyte inflammation by inhibiting NF-κB and WNT /β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) showed anti-inflammatory effects in rat models of osteoarthritis (OA). | ||
| M4764 | taraxasteryl-acetate | Others |
| Taraxasteryl acetate was isolated from sagittal plasmodium and showed a broad spectrum of anti-inflammatory activity. Taraxasteryl acetate can reduce posterior claw edema induced by dextran, yeast glycan and arachidonic acid in rats. Taraxasteryl acetate can be used to study local inflammation. | ||
| M4987 | Procyanidin B4 | Others |
| A series of dimeric procyanidins (1-9) and some related polyphenols (10-15) were chosen as model compounds in a comparative investigation for various biological activities in order to obtain structure-activity relationships. | ||
| M7520 | Brivaracetam | Sodium Channel |
| UCB34714 | ||
| Brivaracetam (UCB 34714) is chemically related to levetiracetam (LEV, Keppra). It possesses a binding affinity for the synaptic vesicle protein 2A (SV2A) ten-fold above that of LEV and also shows an ability to inhibit Na+ channels. | ||
| M9212 | Aramchol | Stearoyl-CoA Desaturase |
| Arachidyl amido cholanoic acid; C20-FABAC; Icomidocholic acid | ||
| Aramchol is a novel fatty acid bile acid coupling agent with oral activity and an inhibitor of SCD1, which acts by inhibiting SCD1 expression in hepatocytes and hepatic astrocytes, and can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M9720 | Aranidipine | Calcium Channel |
| MPC1304; CCRIS-6724 | ||
| Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. | ||
| M10658 | Calenduloside E | HSP |
| Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata. Calenduloside E (CE) has anti-apoptotic potent by targeting heat shock protein 90 (Hsp90). | ||
| M11330 | bpV(phen) trihydrate | PTEN |
| BpV (PHEN) Trihydrate, an insulin mimic, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50 of 38 nM, 343 nM, and 920 nM for PTEN, PTP-β, and PTP-1B. BpV (PHEN) TriHydrate inhibits proliferation of protozoan parasites leishmania in vitro. | ||
| M13772 | Brilliant Blue FCF | Fluorescent Dye |
| Acid Blue 9; FD&C Blue No. 1; E133 | ||
| Brilliant Blue FCF has the appearance of a reddish-blue powder. | ||
| M19444 | Cubebin | Others |
| Cubebin is a dibenzylbutyrolactone lignan isolated from the crude hexane extract of the leaves of Zanthoxyllum naranjillo. Cubebin shows a significant anti-inflammatory activity. | ||
| M21219 | Maralixibat chloride | Others |
| SHP625 chloride; LUM001 chloride; Lopixibat chloride | ||
| Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. (IBAT) is used in the study of rare cholestatic liver diseases, including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. | ||
| M21421 | Upacicalcet | Calcium-sensing Receptor |
| Upacicalcet is a calcium-sensing receptor (CaSR) agonist being developed for the study of secondary hyperparathyroidism (SHPT). | ||
| M21483 | MBC-11 triethylamine | Others |
| MBC-11 triethylamine is the first (first-in-class), bone-targeted ethyl bisphosphonate covalently bound conjugate to the antimetabolite cytarabine (araC). MBC-11 triethylamine has the potential to be used in neoplastic bone disease (TIBD).*The compound is unstable in solutions, freshly prepared is recommended | ||
| M25504 | 1,2-Dierucoyl-sn-glycero-3-phosphocholine | Cell Transfection |
| DEPC; L-Dierucoyl lecithin; Dierucoyllecithin | ||
| 1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity. | ||
| M27605 | Pentamidine | Parasite |
| MP-601205 | ||
| Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. | ||
| M28652 | Paramethasone Acetate | Others |
| Paramethasone acetate is a synthetic glucocorticoid, and shows anti-inflammatory and immunosuppressant activities. | ||
| M28709 | Roginolisib hemifumarate | PI3K |
| MSC2360844 hemifumarate; IOA-244 hemifumarate | ||
| Roginolisib (MSC2360844) hemifumarate is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases. | ||
| M28732 | Sepin-1 | Others |
| Sepin-1 is a potent separase inhibitor with an IC50 value of 14.8 µM. Sepin-1 inhibits cell proliferation, migration and wound healing. Sepin-1 decreases the expression of FoxM1 protein and mRNA level. Sepin-1 shows anti-tumor activity. | ||
| M28866 | GNF6702 | Parasite |
| GNF6702 is a selective inhibitor of the kinetoplastid proteasome. GNF6702 clears parasites in murine models of leishmaniasis, Chagas disease, and human African trypanosomiasis. | ||
| M29176 | F 13714 fumarate | 5-HT Receptor |
| F 14679 fumarate | ||
| F13714 fumarate, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress. | ||
| M30078 | bpV(phen) | PTEN |
| bpV(phen), a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV(phen) inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). bpV(phen) can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity. | ||
| M30478 | Pentamidine dimesylate | Antibiotic |
| MP-601205 dimesylate | ||
| Pentamidine (MP-601205) dimesylate is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dimesylate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dimesylate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dimesylate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. | ||
| M30549 | Xamoterol hemifumarate | Adrenergic Receptor |
| Corwin hemifumarate; ICI 118587 hemifumarate | ||
| Xamoterol hemifumarate is a selective and potent agonist of beta1-adrenergic receptor. Xamoterol hemifumarate has the potential for the research of arrhythmogenesis. Xamoterol hemifumarate has the potential for the investigating the relationship between β1-adrenergic stimulation and IKr. | ||
| M30841 | Droxicam | Others |
| Ombolan | ||
| Droxicam (Ombolan) is a non-steroidal anti-inflammatory agent, with strong analgesic activity. Droxicam acts by inhibiting PGE2 varies, and is characterised by being a pro-drug of Piroxicam. Droxicam is well tolerated with slight side effects in the said mucosa. Droxicam does not show cardiovascular or respiratory effects in cats, and inhibits peritoneal capillary permeability in mouse. | ||
| M31253 | Chitoheptaose | Others |
| Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models. | ||
| M38794 | Cardol diene | Parasite |
| Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability. | ||
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