About 2 results found for searched term "Androgen receptor degrader-3" (0.141 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43589 | Androgen receptor degrader-3 | Androgen Receptor |
| Androgen receptor degrader-3 is an androgen receptor degrader. | ||
| M29317 | UT-34 | Androgen Receptor |
| UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy. | ||
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