Androgen receptor antagonist 8 - Search Results

About 6 results found for searched term "Androgen receptor antagonist 8" (0.127 seconds)

Cat.No.	Name	Target
M43584	Androgen receptor antagonist 8	Androgen Receptor
	Androgen receptor antagonist 8 is an androgen receptor antagonist.
M2717	Galeterone	Androgen Receptor
	TOK-001
	Galeterone is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth.
M10965	ORM-15341	Androgen Receptor
	ORM-15341 is a potent androgen receptor (AR) antagonist that acts on AR-HEK293 cells with an IC50 value of 38 nM.
M28616	Rezvilutamide	Androgen Receptor
	SHR3680
	Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer.
M29317	UT-34	Androgen Receptor
	UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy.
M29958	AR antagonist 3	Androgen Receptor
	AR antagonist 3 is a potent and selective androgen receptor (AR) antagonist with an IC50 of 0.47 µM. AR antagonist 3 exhibits a dose-dependent decrease of the FRET signal (IC50= 18.05 μM). AR antagonist 3 shows effective inhibition on tumor growth when administered intratumorally.