About 13 results found for searched term "Anandamide" (0.335 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13917 | Anandamide | Cannabinoid |
| AEA | ||
| Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). | ||
| M6462 | ARN272 | Others |
| ARN 272 | ||
| ARN272 is a fAAH-like anandamide transporter (FLAT) inhibitor. | ||
| M6465 | Arvanil | TRP Channel |
| Arvanil is a potent CB 1 and TRPV1 agonist. Also anandamide transport inhibitor. | ||
| M7082 | OMDM-2 | Others |
| OMDM-2 is a potent inhibitor of anandamide uptake. | ||
| M7462 | VDM 11 | Others |
| VDM 11 is a potent, selective anandamide transport inhibitor. | ||
| M7591 | Arachidonyl trifluoromethyl ketone | Phospholipase |
| Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A2. | ||
| M11426 | AM404 | Cannabinoid |
| N-(4-HYDROXYPHENYL)-ARACHIDONYLAMIDE | ||
| AM404 is an endocannabinoid reuptake inhibitor that can block anandamide transport with IC50 values in the low mole range. The isolated rat hepatic artery was constricted by norepinephrine and relaxed by AM404. PEC50 value was 7.4 (corresponding EC50 value was 0.04 µM). It has neuroprotective effects. | ||
| M13918 | Synaptamide | Cannabinoid |
| Dehydroepiandrosteron(DHEA); Docosahexaenoyl ethanolamide | ||
| Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. | ||
| M14425 | LY2183240 | FAAH |
| LY2183240 is a highly potent blocker of anandamide uptake (IC50= 270 pM; Ki=540 nM). LY2183240 is a potent, covalent inhibitor of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) with an IC50 of 12.4 nM. | ||
| M14512 | MAFP | Phospholipase |
| Methyl Arachidonyl Fluorophosphonate | ||
| MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor of cPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor of anandamide amidase. | ||
| M29091 | ZCZ011 | Cannabinoid |
| ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain. | ||
| M30475 | Linoleoyl ethanolamide | Cannabinoid |
| Linoleic acid monoethanolamide | ||
| Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time. | ||
| M41790 | O-2093 | Cannabinoid |
| O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM. | ||
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