About 2 results found for searched term "Acalabrutinib" (0.133 seconds)
Cat.No. | Name | Target |
---|---|---|
M5306 | Acalabrutinib | BTK |
ACP-196 | ||
Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR. | ||
M14321 | ACP-5862 | Others |
ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). |
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