About 5 results found for searched term "ATM Inhibitor-8" (0.135 seconds)
Cat.No. | Name | Target |
---|---|---|
M41406 | ATM Inhibitor-8 | ATM/ATR |
ATM Inhibitor-8 is a highly potent, selective and orally active ATM inhibitor,with an IC50 of 1.15 nM. | ||
M9581 | AZD1390 | ATM/ATR |
AZD-1390 | ||
AZD1390 is currently the most effective and highly selective ATM inhibitor with an IC50 of 0.78 nM, oral activity and the ability to cross the blood-brain barrier. In vivo, AZD1390 combined with radiotherapy effectively inhibited tumor growth. | ||
M10130 | AZD0156 | ATM/ATR |
AZD-0156 | ||
AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits ATM mediated signal transduction, prevents DNA damage checkpoint activation, damages DNA damage repair, and induces tumor cell apoptosis. | ||
M13409 | ATM-3507 trihydrochloride | Myosin |
ATM-3507 is a potent inhibitor of Tropomyosin with an IC50 value of 3.83-6.84μM in human melanoma cell lines. | ||
M29641 | ATM-3507 trihydrochloride | Myosin |
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor with IC50s from 3.83-6.84 μM in human melanoma cell lines. |
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