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 About 2 results found for searched term "AOH1160" (0.326 seconds)

Cat.No.  Name Target
M40520 AOH1160 Others
AOH1160 is a potent, first-in-class, orally active inhibitor of proliferating cell nuclear antigen (PCNA) that also interferes with DNA replication, blocks homologous recombination-mediated DNA repair, as well as causes cell cycle arrest and induces apoptosis, and can be used in oncology-related studies.
M40519 AOH1996 DNA/RNA Synthesis
AOH1996 is an orally active small molecule PCNA inhibitor, which can be obtained by adding a methoxy group to the interstitial position of the benzene ring at the end of AOH1160, and enhances the interaction between PCNA and RPB1, the largest subunit of RNA polymerase II, as well as selectively kills cancer cells, which can be used in cancer-related research.



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