About 12 results found for searched term "AM-TS23" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6443 | AM-TS23 | Others |
| AM-TS23 is a dNA polymerase λ and β inhibitor. | ||
| M2388 | Amitriptyline hydrochloride | 5-HT Receptor |
| Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively. | ||
| M4973 | BAPTA-AM | Potassium Channel |
| BAPTA-AM is a selective, membrane-permeable calcium chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively. | ||
| M6441 | AMTB hydrochloride | TRP Channel |
| AMTB hydrochloride is a tRPM8 channel blocker. AMTB hydrochloride inhibits icilin-induced TRPM8 channel activation in a rat model (pIC50 = 6.23). | ||
| M15093 | Recombinant Human EpCAM/Trop1 (Expi293, C-His) | Cytokines and Growth Factors |
| CD326 antigen; CD326; EGP; EGP-2 | ||
| Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. | ||
| M20793 | Amitriptyline | Serotonin Transporter |
| MK-230; N-750; Ro41575 | ||
| Amitriptyline (MK-230, N-750, Ro41575) is an inhibitor of the serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively, and also inhibits the histamine receptor H1, the histamine receptor H4, 5-HT2, and the Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It can also inhibit histamine receptor H1, histamine receptor H4, 5-HT2 and Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively, and can be used in studies of depression and neuropathic pain. | ||
| M27684 | Lazabemide hydrochloride | Monoamine Oxidase |
| Ro 19-6327 hydrochloride | ||
| Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease. | ||
| M28890 | WCK-4234 | Antibiotic |
| WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibits class A, C, and D β-lactamases activity. WCK-4234 lacks direct antibacterial activity. WCK-4234 potentiates imipenem and meropenem against Enterobacteriaceae with OXA-48/OXA-181 or KPC enzymes, or with combinations of impermeability and AmpC or ESBL activity. WCK-4234 distinctively overcomes resistance mediated by OXA-type carbapenemases. | ||
| M29548 | PROTAC PARP1 degrader | PROTAC |
| PROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM. | ||
| M30407 | Asperphenamate | Autophagy |
| Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively. | ||
| M31163 | Recombinant Mouse PPARA Protein (E.coli, His Tag) | Cytokines and Growth Factors |
| Mouse PPAR-alpha | ||
| The recombinant Mouse PPARA consists of 276 amino acids and predicts a molecular mass of 31.49 kDa. A DNA sequence encoding the Mouse PPARA (P23204) (Thr200-Tyr468) was expressed, with a polyhistidine tag at the N-terminus. | ||
| M39077 | Skullcapflavone I | Elastase |
| Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a. | ||
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