About 14 results found for searched term "ALDH" (0.147 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6423 | Alda-1 | ALDH |
| Alda1 | ||
| Alda-1 is a potent and selective Aldehyde Dehydrogenase-2 Agonist. Alda-1 activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. | ||
| M55218 | Aldehyde dehydrogenase | Enzymes & Coenzymes |
| ALDH | ||
| Aldehyde dehydrogenase is a soluble enzyme and its activity depends on potassium ions and cysteine. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems. | ||
| M3390 | Disulfiram | Pyroptosis |
| Tetraethylthiuram disulfide; TETD | ||
| Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1). Disulfiram is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
| M3706 | CVT-10216 | ALDH |
| CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking. | ||
| M6384 | A37 | ALDH |
| A37 is a aLDH1A1 inhibitor. | ||
| M7487 | WIN 18446 | ALDH |
| WIN 18446 is a aLDH1a2 inhibitor, with IC50 of 0.3 μM. | ||
| M25611 | Cyclosomatostatin acetate | Somatostatin Receptor |
| cycloSST | ||
| Cyclosomatostatin acetate is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin acetate can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells. | ||
| M8781 | NCT-501 | ALDH |
| NCT-501 is a potent and selective inhibitor of Aldehyde dehydrogenase ALDH1A1, a dehydrogenase that has been found to be elevated in certain cancers and in cancer stem cells. | ||
| M20768 | CM10 | ALDH |
| CM10 is a potent and selective inhibitor of aldehyde dehydrogenase 1A family (ALDH1A) with IC50 of 1700 nM, 740 nM and 640 nM for ALDH1A1, ALDH1A2 and ALDH1A3, respectively. CM10 exhibits anti-cancer activity. | ||
| M29205 | EN40 | ALDH |
| EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM. | ||
| M29799 | IGUANA-1 free base | ALDH |
| STL5-T-0057 | ||
| IGUANA-1 free base (STL5-T-0057) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research of cancer. | ||
| M29800 | IGUANA-1 | ALDH |
| IGUANA-1 is a potent inhibitor of ALDH1B1, which is a mitochondrial enzyme that promotes colorectal and pancreatic cancer. IGUANA-1 has significant inhibition against cancer cells. | ||
| M31093 | RV01 | ALDH |
| RV01 is a novel quinolyl-substituted analogue of resveratrol, it inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol. RV01 exhibits hydroxyl radical scavenging activity. | ||
| M58106 | NCT-505 | ALDH |
| NCT505 | ||
| NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM. NCT-505 weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57, 22.8, 20.1, >57 μM, respectively. | ||
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