About 6 results found for searched term "AKT-IN-18" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43370 | AKT-IN-18 | Akt |
| AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells. | ||
| M1862 | Ipatasertib (GDC-0068) | Akt |
| Ipatasertib, RG7440 | ||
| GDC-0068 (RG7440) is a potent and selective, ATP-competitive Akt inhibitor with IC50 values of 5 to 18 nM. | ||
| M11228 | BAY1125976 | Akt |
| BAY1125976 is an Akt1/Akt2 selective allosteric inhibitor. The IC50 values of Akt1 and Akt2 inhibition at 10 μM ATP were 5.2 nM and 18 nM, respectively. | ||
| M5324 | GDC-0068 dihydrochloride | Akt |
| Ipatasertib dihydrochloride; RG-7440 dihydrochloride | ||
| GDC-0068(RG 7440) 2Hcl is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, 620-fold selectivity over PKA. | ||
| M6044 | Uprosertib (GSK2141795) | Akt |
| GSK795; Uprosertib | ||
| Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM for Akt1, 328 nM for Akt2, and 38 nM for Akt3 respectively (Clinical phase 1). | ||
| M27712 | Uprosertib hydrochloride | Akt |
| GSK2141795 (hydrochloride) | ||
| Uprosertib hydrochloride (GSK2141795 hydrochloride) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively. | ||
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