About 2 results found for searched term "AKR1C3-IN-10" (0.224 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42283 | AKR1C3-IN-10 | Aldose Reductase |
| AKR1C3-IN-10 is a selective AKR1C3 inhibitor (IC50=51 nM). | ||
| M27975 | S07-2010 | Others |
| S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells. | ||
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