About 6 results found for searched term "AHR agonist 3" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41280 | AHR agonist 3 | Apoptosis |
| AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. | ||
| M7727 | CH-223191 | Aryl hydrocarbon Receptor |
| CH223191 | ||
| CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M10486 | GNF351 | Aryl hydrocarbon Receptor |
| GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. | ||
| M10941 | Tapinarof | Aryl hydrocarbon Receptor |
| WBI-1001; Benvitimod; GSK2894512 | ||
| Tapinarof (WBI-1001) is a Frist in class aromatic hydrocarbon receptor (AhR) agonist with EC50 of 13 nM. Tapinarof reduced skin inflammation in mice. It can effectively inhibit inflammatory cytokines, regulate skin barrier protein expression and antioxidant activity. | ||
| M14603 | Indole-3-carbinol | NF-κB |
| I3C; 3-Indolemethanol | ||
| Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1). | ||
| M21086 | Indole-3-pyruvic acid | Metabolite/Endogenous Metabolite |
| Indole-3-pyruvic acid, a ketone analogue of tryptophan, is an orally active AHR agonist. indole-3-pyruvic acid has antioxidant properties and can be used in studies of inflammation, anxiety. | ||
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