About 2 results found for searched term "AF 353" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3949 | AF 353 | P2 Receptor |
| Ro-4 | ||
| AF-353 is a novel, potent and orally bioavailable P2X3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3. | ||
| M30720 | Mirodenafil dihydrochloride | PDE |
| SK-3530 dihydrochloride | ||
| Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc). | ||
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