About 1 result found for searched term "ADH-6 TFA " (0.456 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31002 | ADH-6 TFA | p53 |
| ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases. | ||
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