About 3 results found for searched term "A2AR antagonist 1" (1.463 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9569 | Etrumadenant | Adenosine Receptor |
| AB928; A2aR/A2bR antagonist-1 | ||
| Etrumadenant (AB928, A2aR/A2bR antagonist-1) is an orally bioavailable, dual antagonist of the A2aR and A2bR adenosine receptors, leads to greater immunomodulatory activity and reduced tumor growth. | ||
| M20627 | A2AR antagonist 1 | Adenosine Receptor |
| A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. | ||
| M40653 | A2AR-antagonist-1 | Adenosine Receptor |
| A2AR-antagonist-1 is an orally active adenosine receptor A2AR antagonist with an IC50 value of 29 nM.A2AR-antagonist-1 is also a T-cell activator that acts by inhibiting immunosuppressive molecules (LAG-3 and TIM-3) and potentiating effector molecules (GZMB, IFNG and IL-2). It has antitumor activity and is metabolically stable in mouse liver microsomes. | ||
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