About 1 result found for searched term "A-769662" (0.064 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3444 | A-769662 | AMPK |
| A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 μM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 μM). | ||
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