About 15 results found for searched term "93-35-6" (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1706 | ENMD-2076 | Aurora Kinase |
| ENMD-2076 is an orally-active, Aurora A/angiogenic kinase inhibitor. | ||
| M8119 | PF-02413873 | Progesterone Receptor |
| PF-02413873 is a potent, selective and fully competitive non-steroidal progesterone receptor (PR) antagonist that blocks progesterone binding and PR nuclear translocation. | ||
| M10493 | MDR-652 | TRP Channel |
| MDR652 | ||
| MDR-652 is a potent and specific transient receptor potential vanilloid 1 (TRPV1) agonist with Ki of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1, respectively. | ||
| M14415 | Umbelliferone | Metabolite/Endogenous Metabolite |
| 7-Hydroxycoumarin; Hydrangin; NSC 19790 | ||
| Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. | ||
| M21530 | Sebetralstat | Serine/Threonine Protease |
| KVD900 | ||
| Sebetralstat is an orally active plasma kininase (KLKB1) inhibitor for studies related to hereditary angioedema (HAE). | ||
| M22512 | EDP-305 | Farnesoid X Receptor |
| EDP305 | ||
| EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 can be used for the research of primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). | ||
| M25293 | Amatuximab | Others |
| MORab-009 | ||
| Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium. | ||
| M25294 | Robatumumab | IGF-1R |
| Sch 717454; 19D12 | ||
| Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research. | ||
| M29034 | SPT-IN-1 | Others |
| SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research. | ||
| M29035 | KIRA-7 | IRE1 |
| KIRA-7, an imidazopyrazine compound, binds the IRE1α kinase (IC50 of 110 nM) to allosterically inhibit its RNase activity. KIRA-7 has an anti-fibrotic effect. | ||
| M30940 | Flobetapir | Others |
| AV-45 | ||
| Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18. | ||
| M39960 | Dehydroglyasperin C | Others |
| Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities. | ||
| M45292 | TBCA | Casein Kinase |
| TBCA is a highly selective inhibitor of casein kinase II CK2 with an IC50 of 110 nM and a Ki of 77 nM.In addition, TBCA exhibits selectivity for CK1, DYRK1A and 27 other kinases. | ||
| M49540 | ROCK-IN-1 | ROCK |
| ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2. | ||
| M52289 | Benzyl (tert-butoxycarbonyl)-L-tyrosinate | Amino Acid Derivatives |
| Benzyl (tert-butoxycarbonyl)-L-tyrosinate is a tyrosine derivative. | ||
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