About 6 results found for searched term "83-40-9" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4306 | Ganoderic-acid-D | Sirtuin |
| Ganoderic acid D is a highly oxidized tetracyclic triterpenoid that is the main active ingredient in Ganoderma lucidum. Ganoderic acid D upregulates protein expression for SIRT3 and induces deacetylated cyclophilic protein D (CypD) through SIRT3. Ganoderic acid D inhibits energy reprogramming in colon cancer cells, including glucose uptake, lactate production, pyruvate, and acetyl-Coenzyme production in colon cancer cells. | ||
| M5362 | 3-Methylsalicylic acid | Metabolite/Endogenous Metabolite |
| o-Cresotic acid; Hydroxytoluic acid | ||
| 3-Methylsalicylic acid is a salicylic acid derivative that acts on human plasma and has significant fibrinolytic activity by activating the fibrinolytic system. | ||
| M8244 | AK-7 | Sirtuin |
| AK7 | ||
| AK-7 is a brain penetrant selective SIRT2 inhibitor, with an IC50 of 15.5 μM. | ||
| M40810 | STX-478 | PI3K |
| STX-478 is a mutation-selective variant PI3Ka inhibitor for studies related to breast cancer and other solid tumors. | ||
| M50217 | TNG348 | Deubiquitinase |
| TNG-348 | ||
| TNG348 is a novel, oral, potent and selective ubiquitin-specific protease 1 (USP1) inhibitor for studies related to BRCA1/2 mutations and other homologous recombination defect (HRD)+ cancers. | ||
| M56790 | ASN06917370 | ROR |
| ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. | ||
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