About 9 results found for searched term "73-03-0" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4290 | Atractylenolide-III | Apoptosis |
| ICodonolactone; 8β-Hydroxyasterolide | ||
| Atractylenolide III (ATL III) is the main component of rhizome of Atractylenolide, which can induce apoptosis of lung cancer cells. | ||
| M4779 | Cordycepin | MMP |
| 3'-Deoxyadenosine | ||
| Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. | ||
| M9020 | TAS-102 | DNA/RNA Synthesis |
| Trifluridine/Tipiracil HCl; Trifluridine-tipiracil hydrochloride mixture | ||
| TAS-102 is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride. | ||
| M10963 | ARCC-4 | Others |
| ARCC-4 is based on PROTAC technology, a nanomolar grade androgen receptor (AR) degrader D50 The value is 5 nM. ARCC-4 is an AR PROTAC recruited by von Hippel-Lindau (VHL) based on enzalutamide. ARCC-4 effectively degrades AR mutations associated with antiandrogen studies. | ||
| M14302 | 2-PMPA | Others |
| 2-(Phosphonomethyl)pentanedioic acid | ||
| 2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. | ||
| M17032 | Cuniloside B | Monoterpenoids |
| Cuniloside B | ||
| M29783 | DS20362725 | Estrogen Receptor |
| DS20362725 is an estrogen-related receptor α (ERRα) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.6 μM. DS20362725 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM). | ||
| M30560 | JNJ10191584 | Histamine Receptor |
| VUF6002 | ||
| JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively. | ||
| M55738 | MC-SN38 | Drug-Linker Conjugates for ADC |
| MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). | ||
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