About 6 results found for searched term "68-95-1" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9142 | FLLL32 | JAK |
| FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM. | ||
| M25098 | Ponsegromab | TGF-beta/Smad |
| PF 06946860 | ||
| Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers. | ||
| M31401 | PAT-347 | PDE |
| PAT-347 is an Autotaxin (ATX) inhibitor. | ||
| M51806 | N-Acetyl-L-proline | Amino Acid Derivatives |
| N-Acetyl-L-proline is aproline derivatives. | ||
| M2825 | Lurasidone hydrochloride | 5-HT Receptor |
| SM-13496 | ||
| Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively. | ||
| M21296 | PF-06843195 | PI3K |
| PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts.The Ki of PF-06843195 acting on PI3Kα and PI3Kδ is less than 0.018 nM and 0.28 nM, respectively.PF-06843195 has a significant inhibitory effect on PI3K/mTOR signaling pathway and had a long-lasting anti-tumor effect. | ||
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