59-48-3 - Search Results | AbMole BioScience

About 6 results found for searched term "59-48-3" (0.058 seconds)

Cat.No.	Name	Target
M4847	Tafamidis	Transthyretin (TTR)
	Fx-1006A, Vyndaqel
	Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade, with EC50s of 2.7-3.2 μM to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR.
M13356	SKI-178	SPHK
	SKI-178 is a potent sphingosine kinase-1 (SphK1) and SphK2 inhibitor. In acute myeloid leukemia (AML) cell lines, the IC50 range is about 500 nm-1 μM. Ski-178 induces apoptosis of human acute myeloid leukemia cells in a CDK1-dependent manner.
M16183	Oxindole	Alkaloids
	Oxindole
M28644	KDM5-C70	Histone demethylase
	KDM5-C70 is an ethyl ester derivative of KDM5-C49 and a potent, cell-permeable and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels.
M52900	[Tyr1]-Somatostatin-14	Somatostatin Receptor
	[Tyr1]-Somatostatin-14 could binds to SSTR2.
M56201	CID1172084	GPR/FFAR
	CID1172084 is a selective GPR55 agonist (EC50=0.16 μM).