About 6 results found for searched term "58-60-6" (0.166 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1946 | CEP-28122 | ALK |
| CEP-28122 is a highly potent and selective orally active ALK inhibitor. | ||
| M6290 | Puromycin aminonucleoside | Apoptosis |
| PAN; 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine | ||
| Puromycin aminonucleoside (PAN), which is an analogue of puromycin antibiotic, has been largely adopted to experimentally induce MCD in rodents (with a single high dose) or FSGS (by repeated doses for over a longer period). | ||
| M17636 | Marsdenoside F | Steroids |
| Marsdenoside F | ||
| M10761 | DC260126 | Apoptosis |
| DC260126 is a potent GPR40 (FFAR1) antagonist. DC260126 dose-dependent inhibits GPR40-mediated Ca of linoleic acid, oleic acid, palm oleic acid, and lauric acid irritation2+ ELEVATED (IC50 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 is protective of palmitate-induced endoplasmic reticulum stress and apoptosis ( apoptosis ) . | ||
| M11015 | FTX-6058 | PRC2/EED |
| FTX-6058 is a potent, orally active embryonic ectodermal development (EED) inhibitor. FTX-6058 can induce HbF protein expression in both cell and murine models. FTX-6058 can be used in the study of specific hemoglobinopathies, including sickle cell disease and β-thalassemia. | ||
| M30560 | JNJ10191584 | Histamine Receptor |
| VUF6002 | ||
| JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively. | ||
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