About 7 results found for searched term "57-47-6" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10476 | GDC-0575 (ARRY-575) | Checkpoint |
| RG7741; ARRY575; AK-687476 | ||
| GDC-0575 (ARRY-575, RG7741) is a potent and selective oral inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. | ||
| M14321 | ACP-5862 | Others |
| ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). | ||
| M27778 | (3S,4S)-Tofacitinib | JAK |
| (3S,4S)-Tofacitinib is the less active S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM. | ||
| M28611 | Benzomalvin A | Neurokinin Receptor |
| Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively. | ||
| M30312 | Physostigmine | AChR/AChE |
| Eserine | ||
| Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning. | ||
| M40093 | Stemonidine | Others |
| Stemonidine is a natural Stemona alkaloid. | ||
| M50514 | Lagatide | Others |
| Lagatide (BN 52080), a heptapeptide, is a short C-terminal analog of sorbin. | ||
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