About 1 result found for searched term "53729-52-5" (1.091 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M19040 | Bruceantinol | STAT |
| Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc. | ||
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