About 8 results found for searched term "53-41-8" (0.195 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5557 | Deferasirox | Cytochrome P450 (e.g. CYP17) |
| CGP-72670, ICL-670 | ||
| Deferasirox (ICL-670) is an iron chelator that causes iron loss that promotes BclxL downregulation and cell death. Deferasirox (ICL-670) also induced P450 3A4 and inhibited 2C8 and 1A2. | ||
| M10939 | Androsterone | Farnesoid X Receptor |
| 5α-Androstan-3α-ol-17-one | ||
| Androsterone is a metabolite of testosterone that activates the farnidol X receptor (FXR). | ||
| M29703 | Dazostinag | STING |
| TAK-676 free base | ||
| Dazostinag (TAK-676 free base) is an agonist of stimulator of interferon genes (STING) protein with antineoplastic activity. Dazostinag can serve as a playload to synthesis antibody-drug conjugates (ADCs). | ||
| M43781 | Salvileucalin A | Others |
| Salvileucalin A is a neo-clerodane related diterpenoid. | ||
| M10965 | ORM-15341 | Androgen Receptor |
| ORM-15341 is a potent androgen receptor (AR) antagonist that acts on AR-HEK293 cells with an IC50 value of 38 nM. | ||
| M28515 | PF-05381941 | p38 MAPK |
| PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC50s of 156 and186 nM, respectively. | ||
| M30190 | GGTI-2418 | Transferase |
| GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors. | ||
| M38647 | 2',3'-Dehydrosalannol | Antibiotic |
| 2',3'-Dehydrosalannol is a potent antibacterial agent, it shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively. | ||
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