About 4 results found for searched term "50-12-4" (0.088 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2320 | 17-AAG (Tanespimycin) | HSP |
| Tanespimycin; 17AAG; NSC 330507; CP 127374 | ||
| 17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50 of 5 nM. Tanespimycin depletes intracellular STK38/NDR1 and decreases STK38 kinase activity. Tanespimycin also downregulated stk38 gene expression. | ||
| M2550 | SB-505124 | TGF-β Receptor |
| Sb-505124 is a selective inhibitor of TGF-βI receptor (ALK4, ALK5, ALK7) with IC50 values of 129 nM and 47 nM for ALK4 and ALK5, respectively. Sb-505124 also inhibits ALK7, but not ALK1, 2, 3 and 6. | ||
| M10855 | Mephenytoin | Others |
| Mephenytoin is an anticonvulsant that is a substrate for CYP2C19 and CYP2B6. | ||
| M29975 | SB-505124 hydrochloride | TGF-β Receptor |
| SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6. | ||
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