About 4 results found for searched term "486-86-2" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4371 | N-Methylcytisine | AChR/AChE |
| N-methylcytisine (Caulophylline) is a tricyclic quinoline alkaloid with hypoglycemic, pain-relieving and anti-inflammatory activities. N-methylcytisine is a selective ligand of the acetylcholine acetylcholine receptor in the central nervous system and has a high affinity for the acetylcholine acetylcholine receptor in the optic ganglion of squid (Kd: 50 nM). | ||
| M13815 | GSK-3484862 | DNA Methyltransferase |
| GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates global demethylation in murine embryonic stem cells. | ||
| M28634 | PF-06648671 | Gamma-secretase/Beta-secretase |
| PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease. | ||
| M29121 | JNJ-56022486 | GluR |
| JNJ-56022486 is an orally active and potent negative AMPA receptor modulator (Ki=19 nM) selective for TARP-γ8. JNJ-56022486 is also a TARP-γ8 receptor antagonist, with blood brain barrier (BBB) permeability. JNJ-56022486 can be used for research of Epilepsy. | ||
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