About 7 results found for searched term "370-50-3" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M57664 | Sorafenib Impurity I | Others |
| Sorafenib Impurity I | ||
| M13946 | SCH 563705 | CXCR |
| SCH 563705 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively. | ||
| M19276 | Rotundine | 5-HT Receptor |
| (-)-Tetrahydropalmatine; L-Tetrahydropalmatine | ||
| Rotundine is an antagonist of 5-HT1A with an IC50 of 370 nM. Rotundine is also an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. | ||
| M29109 | AZ13705339 | PAK |
| AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers. | ||
| M31006 | AZ13705339 hemihydrate | PAK |
| AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers. | ||
| M56819 | Befloxatone | Monoamine Oxidase |
| Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). | ||
| M56721 | UK-370106 | MMP |
| UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. | ||
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