About 1 result found for searched term "3483-11-2" (0.209 seconds)
Cat.No. | Name | Target |
---|---|---|
M59121 | Lithium acetoacetate | Metabolite/Endogenous Metabolite |
Acetoacetic acid lithium | ||
Lithium acetoacetate (Acetoacetic acid lithium) is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Lithium acetoacetate induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. |
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