About 1 result found for searched term "2377858-38-1" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M66403 | SCR130 | DNA/RNA Synthesis |
| SCR130 is a SCR7-based DNA nonhomologous end-joining (NHEJ) inhibitor. SCR130 inhibits the end-joining of DNA in a Ligase IV-dependent manner. SCR130 was specific to Ligase IV, it showed minimal or no effect on Ligase III and Ligase I mediated joining. Importantly, SCR130 exhibited the least cytotoxicity in Ligase IV-null cell line as compared with wild type, confirming Ligase IV-specificity. | ||
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