About 1 result found for searched term "2229037-19-6" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29384 | TL13-112 | PROTAC |
| TL13-112 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.14 nM. TL13-112 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 8550 nM, 42.4 nM, 25.4 nM, and 677 nM, respectively. TL13-112 is comprised of the conjugation of Ceritinib and the Cereblon ligand of Pomalidomide. | ||
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