About 1 result found for searched term "2229037-04-9" (0.145 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29383 | TL13-12 | PROTAC |
| TL13-12 is a potent and selective ALK-PROTAC degrader and inhibits ALK activity with an IC50 value of 0.69 nM. TL13-12 also prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 13.5 nM, 5.74 nM, 18.4 nM, and 65 nM, respectively. TL13-12 is comprised of the conjugation of TAE684 and the Cereblon ligand of Pomalidomide. | ||
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