About 1 result found for searched term "1903768-17-1" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10145 | Danicopan (ALXN2040) | Complement System |
| ACH-4471; ACH-0144471; ALXN2040 | ||
| Danicopan (ALXN2040, ACH-4471, ACH-0144471) is a first-in-class, potent, selective, orally active inhibitor of complement factor D with a Kd value of 0.54 nM for human Factor D. Danicopan can Selectively inhibits key complement factor D in the alternative pathway, blocking C3 convertase production and inhibiting alternative pathway activity. It also prevents the deposition of C3b fragments on blood erythrocytes and inhibits erythrocyte catabolism and extravascular hemolysis. | ||
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