About 1 result found for searched term "1685235-41-9" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28808 | Dyrk1A-IN-5 | DYRK |
| Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with an IC50 of 2.1 μM. Dyrk1A-IN-5 can be used for Down syndrome research. | ||
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