About 3 results found for searched term "150-25-4" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M5135 | Ro-46-2005 | Endothelin Receptor |
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM. | ||
M6506 | Bicine | Others |
Bicine is a general purpose buffer. | ||
M10880 | Rineterkib hydrochloride | ERK |
Rineterkib hydrochloride (compound B) is an orally active inhibitor of ERK1/2 that exerts an antiproliferative effect by activating mutations in the MAPK pathway. This activity is particularly associated with KRAS-mutant non-small cell lung cancer, BRAF-mutant non-small cell lung cancer, KRAS-mutant pancreatic cancer, KRAS-mutant colon cancer, and KRAS mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF. |
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