About 1 result found for searched term "1446321-46-5" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M9778 | Voxelotor | Others |
GBT440 | ||
Voxelotor (GBT 440) is a first-in-class, potent polymeric inhibitor of sickle hemoglobin (HbS). Voxelotor (GBT440) binds to the N-terminal a chain of haemoglobin (Hb), increases haemoglobin S (HbS) affinity for oxygen, delays in vitro HbS polymerization and prevents sickling of red blood cells (RBCs). |
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