About 1 result found for searched term "1429179-07-6" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11277 | IDH889 | Isocitrate Dehydrogenase (IDH) |
| IDH889 is an orally available, brain permeable, allosteric and mutation-specific inhibitor of isocitrate dehydrogenase (IDH1). IDH889 showed high selectivity against IDH1R132 * mutant, with IC50 values of 0.02 μM, 0.072 μM and 1.38 μM against IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 showed high inhibition of intracellular 2-Hg level with IC50 value of 0.014 μM. | ||
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