About 2 results found for searched term "130-16-5" (0.119 seconds)
Cat.No. | Name | Target |
---|---|---|
M4922 | Cloxiquine | Antibiotic |
5-Chloro-8-quinolinol; Dermofungin | ||
Cloxiquine (5-chloro-8-quinolinol) has antibacterial, anti-fungal and anti-amoeba properties. Cloxiquine could be used to study tuberculosis and skin diseases. Cloxiquine also inhibits the growth and metastasis of melanoma cells by activating PPARγ. | ||
M29173 | GSK3494245 | Parasite |
DDD01305143 | ||
GSK3494245 (DDD01305143) is a potent, orally active, and selective inhibitor of the chymotrypsin-like activity of the parasite proteasome binding in a site sandwiched between the β4 and β5 subunits (IC50=0.16 μM for WT L. donovani proteasomes). GSK3494245 moderately inhibits chymotrypsin-like activity of human proteasome (IC50: purified 26S=13 µM; enriched THP-1 extracts IC50=40µM). GSK3494245 exhibits attractive biological and biosafety properties. |
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