About 1 result found for searched term "1281681-33-1" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28112 | VP3.15 dihydrobromide | PDE |
| VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). | ||
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