About 1 result found for searched term "1256580-46-7" (0.13 seconds)
Cat.No. | Name | Target |
---|---|---|
M1942 | Alectinib | ALK |
CH5424802; AF802 | ||
Alectinib (CH5424802) is a highly selective, orally active and potent ALK inhibitor with IC50 of 1.9 nM. Alectinib (CH5424802) also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration. |
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