About 5 results found for searched term "125-10-0" (0.159 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40084 | Glycyroside | Others |
| Glycyroside is a isoflavone diglycoside isolated from Glycyrrhiza eurycarpa P. C. Li. | ||
| M40794 | Prednisone acetate | Animal Modeling |
| Prednisone 21-acetate | ||
| Prednisone acetate is the acetate form of Prednisone and a glucocorticoid receptor agonist with anti-inflammatory and immunomodulatory properties. It can be used to construct animal models of Kawasaki disease. | ||
| M10956 | PAT-1251 | Monoamine Oxidase |
| PAT-1251 is a potent, selective, orally lysanyl oxidase-like protein 2 (LOXL2) inhibitor of hLOXL2 and hLOXL3 IC50 The values were 0.71 and 1.17 μM, respectively, and the inhibition of LOXL2 in mice, rats, and dogs was strong.IC50 Values are 0.10, 0.12, and 0.16 μM, respectively; PAT-1251 can be used for studies of a variety of fibrous diseases. | ||
| M20606 | SAR125844 | c-Met |
| SAR125844 is a potent intravenously active and highly selective MET kinase inhibitor, displaying nanomolar activity against the wild-type kinase (IC50 value of 4.2 nmol/L) and H1094Y, Y1235D, M1250T, L1195V, and D1228H kinase domain mutants (IC50 values of 0.22, 1.7, 6.5, 65, and 81 nmol/L, respectively). | ||
| M29821 | HS-276 | IRAK |
| HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research. | ||
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