About 1 result found for searched term "1240494-13-6" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28022 | SX-517 | CXCR |
| SX-517 is a dual CXCR2/1 antagonist, containing boronic acid. SX-517 inhibits CXCL1-induced Ca2+ flux (IC50=38 nM), and antagonizes CXCL8-induced [(35)S]GTPγS binding (IC50=60 nM) and ERK1/2 phosphorylation. SX-517 has significant ability for inflammation suppression, in both humanized polymorphonuclear (PMN) cells and in murine model. | ||
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