About 1 result found for searched term "114899-77-3" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21415 | Trabectedin | ROS |
| Ecteinascidin 743; ET-743 | ||
| Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies. | ||
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