About 1 result found for searched term "1119276-80-0" (0.376 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45151 | Lifitegrast sodium | Integrin |
| SAR 1118 sodium; SHP-606 sodium | ||
| Lifitegrast sodium is a potent integrin antagonist that blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen (LFA-1) and interrupts the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits the attachment of Jurkat T cells to ICAM-1 with an IC50 of 2.98 nM.May be useful in studies related to dry eye. | ||
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